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19/07/2018 · Experts share four things patients should know about the recent recall by the FDA and 22 countries of several blood pressure and heart drugs containing valsartan, including alternatives and a possible cancer risk. Valsartan Recall Due To Cancer Risk. The FDA has issued a recall for Diovan, Diovan HCT, Exforge, Exforge HCT and Entresto from multiple manufacturers. Researchers discovered that these drugs could be contaminated with N-nitrosodimethylamine or NDMA. NDMA can cause liver cancer. About Valsartan. ENTRESTO is indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure NYHA Class II-IV and reduced ejection fraction. ENTRESTO is usually administered in conjunction with other heart failure therapies, in place of an ACE inhibitor or other ARB.

19/07/2018 · Regulators recall valsartan after finding impurity tied to cancer risk. The cancer-causing compound N-nitrosodimethylamine NDMA. Valsartan is also contained in Novartis' new heart drug Entresto, which pairs the API with sacubitirl in a film-coated tablet. Largest Class I Recall Means Millions of Americans Possibly Exposed to Cancer-Causing Chemical. The recall of dozens of lots of valsartan-, losartan-, and irbesartan-containing drugs has become the FDA’s largest class I recalls in its history. 17/07/2018 · "This recall is due to an impurity, N-nitrosodimethylamine NDMA, which was found in the recalled products, the FDA said in a statement. "However, not all products containing valsartan are being recalled." Officials say NDMA is classified as a probable human carcinogen—a substance that could cause cancer. Valsartan lawsuits are filed by patients who developed various forms of cancer after taking the generic blood pressure medication. Manufacturers have found probable cancer-causing impurities in valsartan-containing products, possibly paving the way for more valsartan recall lawsuits. 05/07/2018 · ENTRESTO ® sacubitril. Further information about this recall is available by calling Novartis at 888-NOW-NOVA 888-669-6682. To learn more about the Sandoz products affected by this recall and requiring corrective action, please click here to be redirected to the Sandoz website.

19/07/2018 · "I am certainly concerned, but I think it is too soon to panic. This recall is a precaution for safety." To put the recall in perspective, Dr. Howard Weintraub, a cardiologist and professor of medicine at NYU Langone Health, said that he told his patients about a meta-analysis study on angiotensin receptor blockers in general and cancer risk. This recall does NOT impact any Novartis or Sandoz valsartan products in the United States. Novartis and Sandoz are committed to meeting the highest quality standards for all of our marketed products, and the recall outside the United States is being conducted. 09/07/2018 · Several heart drugs containing valsartan are being recalled in Europe and Asia after a Chinese active ingredient manufacturer found residues of a substance in its supplies that could cause cancer. EMA recalls heart medicine valsartan made by Chinese firm over potential cancer-causing residue FiercePharma.

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